Distribution of COL8A2 and COL8A1 gene variants in Caucasian primary open angle glaucoma patients with thin central corneal thickness

@inproceedings{Desronvil2010DistributionOC,
  title={Distribution of COL8A2 and COL8A1 gene variants in Caucasian primary open angle glaucoma patients with thin central corneal thickness},
  author={Theodora Desronvil and D. Logan-Wyatt and Wael Abdrabou and Manuel Hern{\'a}ndez Triana and Richard D Jones and Shahla Taheri and E. Del Bono and Louis R Pasquale and Mairesse Olivier and Jonathan L. Haines and B. J. Fan and J L Wiggs},
  booktitle={Molecular vision},
  year={2010}
}
PURPOSE One approach to identify genes that contribute to common complex ocular disorders such as primary open angle glaucoma (POAG) is to study the genetic determinates of endophenotypes that are defined by underlying pre-disposing heritable quantitative traits such as central corneal thickness (CCT). Collagen VIII is a major component of Descemet's membrane and studies in mice have indicated that targeted inactivation of the genes encoding the collagen type 8 alpha1 (Col8a1) and collagen type… CONTINUE READING
Highly Cited
This paper has 20 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

An Updated Review on the Genetics of Primary Open Angle Glaucoma

International journal of molecular sciences • 2015
View 1 Excerpt
Highly Influenced

Microarray analysis of oral mucosal epithelial cell sheet

Tissue Engineering and Regenerative Medicine • 2013
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 42 references

No pathogenic mutations identified in the COL8A1 and COL8A2 genes in familial Fuchs corneal dystrophy.

Investigative ophthalmology & visual science • 2006
View 6 Excerpts
Highly Influenced