Distribution of Auditory and Visual Naming Sites in Nonlesional Temporal Lobe Epilepsy Patients and Patients with Space‐Occupying Temporal Lobe Lesions

@article{Hamberger2007DistributionOA,
  title={Distribution of Auditory and Visual Naming Sites in Nonlesional Temporal Lobe Epilepsy Patients and Patients with Space‐Occupying Temporal Lobe Lesions},
  author={Marla J Hamberger and Shearwood McClelland and Guy Mckhann and Alicia C. Williams and Robert R. Goodman},
  journal={Epilepsia},
  year={2007},
  volume={48}
}
Summary:  Purpose: Current knowledge regarding the topography of essential language cortex is based primarily on stimulation mapping studies of nonlesional epilepsy patients. We sought to determine whether space‐occupying temporal lobe lesions are associated with a similar topography of language sites, as this information would be useful in surgical planning. 
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62 Citations
Highly Influential Citations
5
Background Citations
22
Methods Citations
2
Results Citations
5

62 Citations

Four‐dimensional functional cortical maps of visual and auditory language: Intracranial recording
TLDR
By averaging naming‐related high‐gamma activity at nonepileptic regions across a large number of patients, functional cortical atlases animating the neural dynamics supporting visual‐object and auditory‐description naming at the whole brain level are provided.
Cortical stimulation mapping for localization of visual and auditory language in pediatric epilepsy patients.
TLDR
There was no single area critical for language in more than 50% of patients tested in either modality for which more than 1 patient was tested, affirming that language function is plastic in the setting of dominant-hemisphere pathology.
The Boston Naming Test as a predictor of post-surgical naming dysfunctions in temporal lobe epilepsy
TLDR
The BNT was a good predictor for possible post-surgical language deficits in patients submitted to left temporal lobectomy, and it was found that patients that undergo epilepsy surgery for temporal lobe epilepsy in the dominant hemisphere are more susceptible to naming deficits.
Evidence for cortical reorganization of language in patients with hippocampal sclerosis.
TLDR
Results suggest that preserved naming ability in HS patients following anterior temporal resection might be attributable, at least in part, to intrahemispheric reorganization of language in response to the likely, early development of sclerosis in the medial temporal region.
Multimodality word-finding distinctions in cortical stimulation mapping.
TLDR
Distinct cortical areas were found for distinct input modalities, with language sites in anterior tip regions found most often by using auditory naming, suggesting that a multimodality approach may be needed to spare crucial language sites.
Cortical Language Mapping in Epilepsy: A Critical Review
TLDR
The literature on topographical patterns of language organization inferred from ESM is reviewed, and the influence of patient characteristics on these patterns, including baseline ability level, age, gender, pathology, degree of language lateralization and bilingualism is reviewed.
Sub‐patterns of language network reorganization in pediatric localization related epilepsy: A multisite study
TLDR
The findings suggest a different, perhaps less efficient, cognitive strategy for LRE group to perform the task, and a data‐driven method for fMRI activation pattern separation is independent of a priori notions and bias inherent in region of interest and visual analyses.
Functional Magnetic Resonance Imaging of Language in Epilepsy
TLDR
The use of fMRI for mapping language in epilepsy patients prior to surgical intervention is described including a discussion of methodological issues and task design, comparisons between fMRI and the intracarotid sodium amobarbital test, and fMRI studies of language reorganization.
Multimodal imaging of language reorganization in patients with left temporal lobe epilepsy
Language Organization and Reorganization in Epilepsy
TLDR
Clinical variables have been shown to contribute to cerebral language reorganization in the setting of chronic seizure disorders, yet such factors have not been reliable predictors of altered language networks in individual patients, underscoring the need for language lateralization and localization procedures when definitive identification of language cortex is necessary for clinical care.
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