Distribution of ApoA-I-containing HDL subpopulations in patients with coronary heart disease.

  title={Distribution of ApoA-I-containing HDL subpopulations in patients with coronary heart disease.},
  author={Bela F. Asztalos and Paul S. Roheim and Rodolfo Milani and Michael Lefevre and Judith McNamara and Katalin V. Horvath and Ernst J. Schaefer},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={20 12},
High density lipoproteins (HDLs) and their subspecies play a role in the development of coronary heart disease (CHD). HDL subpopulations were measured by 2-dimensional nondenaturing gel electrophoresis in 79 male control subjects and 76 male CHD patients to test the hypothesis that greater differences in apolipoprotein (apo)A-I-containing HDL subpopulations would exist between these 2 groups than for traditional lipid levels. In CHD subjects, HDL cholesterol (HDL-C) was lower (-14%, P<0.001… CONTINUE READING


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