Distribution of 5HT2A receptors in the human brain: comparison of data in vivo and post mortem.

@article{Forutan2002DistributionO5,
  title={Distribution of 5HT2A receptors in the human brain: comparison of data in vivo and post mortem.},
  author={Farhad Forutan and Sorour Estalji and Markus Beu and Susanne Nikolaus and Kurt Hamacher and Heinz Hubert Coenen and Henning Vosberg and H. W. Mueller-Gaertner and Rolf Larisch},
  journal={Nuklearmedizin. Nuclear medicine},
  year={2002},
  volume={41 4},
  pages={197-201}
}
AIM The study presented here firstly compares the distribution of the binding potential of the serotonin-5HT2A receptor as measured in vivo with data of receptor density taken from literature. Secondly, the sensitivity of the method to detect gradual differences in receptor densities is evaluated. METHODS Positron emission tomography (PET) studies were carried out in 6 healthy volunteers using the selective serotonin-5HT2A ligand 18F-altanserin. The binding potential was quantified in 12… CONTINUE READING