Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues

@article{Martel1992DistributionO1,
  title={Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues},
  author={C. Martel and E. Rh{\'e}aume and M. Takahashi and C. Trudel and F. Labrie},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={1992},
  volume={41},
  pages={597-603}
}
  • C. Martel, E. Rhéaume, +2 authors F. Labrie
  • Published 1992
  • Biology
  • The Journal of Steroid Biochemistry and Molecular Biology
  • Abstract The interconversion of estrone (E1) and 17β-estradiol (E2), androstenedione (4-ene-dione) and testosterone (T), as well as dehydroepiandrosterone and androst-5-ene-3β,17β-diol is catalyzed by 17β-hydroxysteroid dehydrogenase (17β-HSD). The enzyme 17β-HSD thus plays an essential role in the formation of all active androgens and estrogens in gonadal as well as extragonadal tissues. The present study investigates the tissue distribution of 17β-HSD activity in the male and female rat as… CONTINUE READING
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