Distribution of [3H]zolpidem binding sites in relation to messenger RNA encoding the alpha 1, beta 2 and gamma 2 subunits of GABAA receptors in rat brain.

@article{Duncan1995DistributionO,
  title={Distribution of [3H]zolpidem binding sites in relation to messenger RNA encoding the alpha 1, beta 2 and gamma 2 subunits of GABAA receptors in rat brain.},
  author={Gary E. Duncan and George R. Breese and Hugh E. Criswell and T. J. Mccown and Jane S. Herbert and Leslie L. Devaud and A Leslie Morrow},
  journal={Neuroscience},
  year={1995},
  volume={64 4},
  pages={
          1113-28
        }
}
Localization of the messenger RNAs that encode the alpha 1, beta 2 and gamma 2 subunits of GABAA showed a distinct topographic pattern in rat brain which corresponded with [3H]zolpidem binding in most brain regions. The close topographic correspondence between the specific receptor subunits examined and the distribution of [3H]zolpidem binding sites provides support for the hypothesis that this benzodiazepine type 1 selective ligand binds to a GABAA receptor that consists of alpha 1, beta 2 and… CONTINUE READING

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