Distribution and turnover of cholesterol in humans.

  title={Distribution and turnover of cholesterol in humans.},
  author={Paul John Nestel and H M Whyte and Dewitt S. Goodman},
  journal={The Journal of clinical investigation},
  volume={48 6},
The relationships between some parameters of cholesterol metabolism and body weight were studied in 22 subjects. Cholesterol-4-(14)C, complexed with plasma lipoprotein, was injected intravenously and from the resultant specific activity-time curves a number of indexes of cholesterol turnover were calculated. These were based on the two-pool model previously described by Goodman and Noble and included estimates of the sizes of the two pools, the production rate of cholesterol in the system, the… CONTINUE READING
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