Distribution and molecular forms of brain natriuretic peptide in the central nervous system, heart and peripheral tissue of rat.

@article{Aburaya1989DistributionAM,
  title={Distribution and molecular forms of brain natriuretic peptide in the central nervous system, heart and peripheral tissue of rat.},
  author={M Aburaya and Naoto Minamino and Jun Hino and Kenji Kangawa and Hisayuki Matsuo},
  journal={Biochemical and biophysical research communications},
  year={1989},
  volume={165 2},
  pages={880-7}
}
The amino acid sequence of rat brain natriuretic peptide (rBNP) precursor has recently been deduced by the cDNA cloning method (1). In the present study, a radioimmunoassay (RIA) system for rBNP was newly established, and regional distribution of rBNP in the central nervous system, heart and other peripheral tissue of rat was investigated. In heart, especially in cardiac atrium, a high concentration of immunoreactive (ir-) rBNP was detected and identified as rBNP-45 and gamma-rBNP. No… CONTINUE READING