Distribution and metabolism of ingested NO3- and NO2- in germfree and conventional-flora rats.

@article{Witter1979DistributionAM,
  title={Distribution and metabolism of ingested NO3- and NO2- in germfree and conventional-flora rats.},
  author={James Witter and Edward J Balish},
  journal={Applied and environmental microbiology},
  year={1979},
  volume={38 5},
  pages={
          861-9
        }
}
Germfree and conventional-flora Sprague-Dawley rats were fed sodium nitrate or sodium nitrite in their drinking water (1,000 microgram/ml), and various organs, tissues, and sections of the intestinal tract were assayed for nitrate (NO3-) and nitrite (NO2-) by a spectrophotometric method. When fed NO3-, germfree rats had chemically detectable levels of NO3- (only) in the stomach, small intestine, cecum, and colon. Conventional-flora rats fed NO3- had both NO3- and NO2- in the stomach, but only… CONTINUE READING

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