Distribution and genetic characterization of Mycobacterium chelonae in laboratory zebrafish Danio rerio.

@article{Whipps2008DistributionAG,
  title={Distribution and genetic characterization of Mycobacterium chelonae in laboratory zebrafish Danio rerio.},
  author={Christopher M Whipps and Jennifer L. Matthews and Michael L Kent},
  journal={Diseases of aquatic organisms},
  year={2008},
  volume={82 1},
  pages={45-54}
}
During routine screening of zebrafish at a research facility, histological changes consistent with mycobacteriosis were observed, prompting an investigation to determine the background prevalence and distribution of Mycobacterium species throughout the facility. Infection status was evaluated in 240 zebrafish representing 9 genetic lines, using histology, culture and PCR. Environmental sources were also tested for the presence of mycobacteria. Prevalence in zebrafish by culture and PCR was 10… CONTINUE READING