Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: A whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer’s disease patients

@article{Gulys2012DistributionAB,
  title={Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: A whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer’s disease patients},
  author={B. Guly{\'a}s and C. Spenger and Zsuzsa Beliczai and K. Gulya and C. Halldin},
  journal={Neurochemistry International},
  year={2012},
  volume={60},
  pages={153-162}
}
  • B. Gulyás, C. Spenger, +2 authors C. Halldin
  • Published 2012
  • Biology, Medicine
  • Neurochemistry International
  • One of the major pathological landmarks of Alzheimer's disease and other neurodegenerative diseases is the presence of amyloid deposits in the brain. The early non-invasive visualization of amyloid is a major objective of recent diagnostic neuroimaging approaches, including positron emission tomography (PET), with an eye on follow-up of disease progression and/or therapy efficacy. The development of molecular imaging biomarkers with binding affinity to amyloid in the brain is therefore in the… CONTINUE READING
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