Distributed structures underlie gating differences between the kin channel KAT1 and the Kout channel SKOR.

@article{Riedelsberger2010DistributedSU,
  title={Distributed structures underlie gating differences between the kin channel KAT1 and the Kout channel SKOR.},
  author={Janin Riedelsberger and T. Sharma and Wendy Gonz{\'a}lez and Pawel Gajdanowicz and Samuel El{\'i}as Morales-Navarro and Carlos Garc{\'i}a-Mata and Bernd Mueller-Roeber and Fernando D Gonz{\'a}lez-Nilo and Michael R Blatt and Ingo Dreyer},
  journal={Molecular plant},
  year={2010},
  volume={3 1},
  pages={236-45}
}
The family of voltage-gated (Shaker-like) potassium channels in plants includes both inward-rectifying (K(in)) channels that allow plant cells to accumulate K(+) and outward-rectifying (K(out)) channels that mediate K(+) efflux. Despite their close structural similarities, K(in) and K(out) channels differ in their gating sensitivity towards voltage and the extracellular K(+) concentration. We have carried out a systematic program of domain swapping between the K(out) channel SKOR and the K(in… CONTINUE READING
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