• Corpus ID: 240353894

Distributed model order reduction of a model for microtubule-based cell polarization using HAPOD

  title={Distributed model order reduction of a model for microtubule-based cell polarization using HAPOD},
  author={Tobias Leibner and Maja Matis and Mario Ohlberger and Stephan Rave},
In this contribution we investigate in mathematical modeling and efficient simulation of biological cells with a particular emphasis on effective modeling of structural properties that originate from active forces generated from polymerization and depolymerization of cytoskeletal components. In detail, we propose a nonlinear continuum approach to model microtubule-based forces which have recently been established as central components of cell mechanics during early fruit fly wing development… 

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