Distraction osteogenesis in the irradiated canine mandible.

@article{Gantous1994DistractionOI,
  title={Distraction osteogenesis in the irradiated canine mandible.},
  author={Andres Gantous and John D. Phillips and Pamela Catton and Daniel Holmberg},
  journal={Plastic and reconstructive surgery},
  year={1994},
  volume={93 1},
  pages={164-8}
}
The potential use of distraction osteogenesis in mandibular reconstruction has been limited by its questionable efficacy in previously radiated bone. We studied five mongrel dogs that had a hemimandible rendered edentulous and underwent a full course of external beam radiation therapy (50 Gy/20 fractions). Six months after completion of radiotherapy, a 2-cm critical-size segmental mandibular defect was created and stabilized with a stainless steel plate. A proximal mandibular transport segment… CONTINUE READING

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