Distraction bone healing versus osteotomy healing: a comparative biochemical analysis.

  title={Distraction bone healing versus osteotomy healing: a comparative biochemical analysis.},
  author={J. M. G. Lammens and Zhaowei Liu and Jeroen Aerssens and Jan Dequeker and Guy Fabry},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  volume={13 2},
This study investigates the biochemical changes in a canine tibia lengthening model in comparison with a nonlengthened osteotomy model. The lengthened and the osteotomized callus and a contralateral corresponding segment were analyzed for their mineralization profile, collagen content, osteocalcin, insulin-like growth factor I (IGF-I), and transforming growth factor beta1 (TGF-beta1). Examinations of bone samples were performed using specimens excised at different time intervals (respectively… CONTINUE READING
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