Distraction Osteogenesis of the Lower Extremity in Patients With Achondroplasia/Hypochondroplasia Treated With Transplantation of Culture-Expanded Bone Marrow Cells and Platelet-Rich Plasma

@article{Kitoh2007DistractionOO,
  title={Distraction Osteogenesis of the Lower Extremity in Patients With Achondroplasia/Hypochondroplasia Treated With Transplantation of Culture-Expanded Bone Marrow Cells and Platelet-Rich Plasma},
  author={Hiroshi Kitoh and Takahiko Kitakoji and Hiroki Tsuchiya and Mitsuyasu Katoh and Naoki Ishiguro},
  journal={Journal of Pediatric Orthopaedics},
  year={2007},
  volume={27},
  pages={629-634}
}
Background: Longer treatment period in distraction osteogenesis (DO) of the lower extremity leads to more frequent complications. We have developed a new technique of transplantation of culture-expanded bone marrow cells (BMCs) and platelet-rich plasma (PRP) during DO to accelerate new bone formation. To assess the efficacy of this cell therapy, retrospective comparative study was conducted between the bones treated with BMC and PRP and the bones treated without BMC and PRP during DO in… Expand
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