Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse

@article{Li1999DistortionPO,
  title={Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse},
  author={Daqing Li and Charles Michael Henley and Bert W. O’Malley},
  journal={Hearing Research},
  year={1999},
  volume={138},
  pages={65-72}
}
Thyroid hormone plays an important role in hearing development. Hereditary hypothyroidism is frequently associated with sensorineural hearing loss as identified in both animal models and human patients. Building upon our original demonstration of congenital deafness and hair cell abnormality in a hyt/hyt mouse model which carries an autosomal recessive mutation causing hereditary hypothyroidism, we investigated the functional capacity of the outer hair cell (OHC) system in these animals using… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

Hearing loss in HDR syndrome: a study of mice and men

VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Cochlear dysfunction in patients with acute hypothyroidism

  • European Archives of Oto-Rhino-Laryngology
  • 2012
VIEW 1 EXCERPT
CITES RESULTS

Deafness and permanently reduced potassium channel gene expression and function in hypothyroid Pit1dw mutants.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2009
VIEW 2 EXCERPTS
CITES BACKGROUND