Distinguishing vaccine efficacy and effectiveness.

  title={Distinguishing vaccine efficacy and effectiveness.},
  author={Eunha Shim and Alison P. Galvani},
  volume={30 47},
BACKGROUND Mathematical models of disease transmission and vaccination typically assume that protective vaccine efficacy (i.e. the relative reduction in the transmission rate among vaccinated individuals) is equivalent to direct effectiveness of vaccine. This assumption has not been evaluated. METHODS We used dynamic epidemiological models of influenza… CONTINUE READING