Distinguishing schizophrenia from posttraumatic stress disorder with psychosis

  title={Distinguishing schizophrenia from posttraumatic stress disorder with psychosis},
  author={Aengus {\'O}Conghaile and Lynn E. DeLisi},
  journal={Current Opinion in Psychiatry},
Purpose of review Co-occurrence of psychotic symptoms with symptoms typically thought of as posttraumatic stress disorder (PTSD) is well known, and there has been considerable debate whether this represents a psychotic subtype or a comorbid psychotic disorder. Recent findings Psychotic symptoms typical of schizophrenia occur with a higher than expected frequency in PTSD. A large genome-wide association study (GWAS) has identified a collection of genes associated with PTSD, and these genes… 
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Psychotic features and combat‐associated PTSD
  • M. Hamner
  • Psychology, Medicine
    Depression and anxiety
  • 1997
In a prospective study, combat associated PTSD patients were administered clinical ratings, including the Structured Clinical Interview for DSM‐III‐R with psychotic screen (SCID‐P), Clinician Administered PTSD Scale (CAPS) and the Impact of Events Scale (IES).
Psychotic features in chronic posttraumatic stress disorder and schizophrenia: comparative severity.
Compared with patients with schizophrenia, veterans meeting DSM-IV criteria for chronic PTSD with well-defined comorbid psychotic features or chronic schizophrenia were remarkably similar with respect to not only positive but also negative symptoms.
Family history study of posttraumatic stress disorder with secondary psychotic symptoms.
PTSD with secondary psychotic symptoms was not associated with familial psychosis, suggesting it does not reflect the presence of an underlying psychotic disorder.
The comorbidity of psychotic symptoms and posttraumatic stress disorder: evidence for a specifier in DSM-5.
Clinical implications are offered, including the suggestion that the next edition of the Diagnostic and Statistical Manual of Mental Disorders includes a specifier of PTSD with psychotic features.
Co-occurrence of posttraumatic stress disorder with positive psychotic symptoms in a nationally representative sample.
This is the first population-based study to investigate PTSD in relation to endorsement of positive psychotic symptoms, and a strong association was obtained.
Trauma and Posttraumatic Stress Disorder (PTSD) in Patients with Schizophrenia or Schizoaffective Disorder
Clear evidence of under-report of trauma and under-diagnosis of PTSD in patients’ charts is shown, and the finding of negative posttraumatic cognitions suggests that the cognitive model of PTSD may be applicable to patients with schizophrenia or schizoaffective disorder.
PTSD and Comorbid Psychotic Disorder: Comparison with Veterans Diagnosed with PTSD or Psychotic Disorder
Veterans with PTSD and a comorbid psychotic disorder showed significantly higher levels of positive symptoms of psychosis, general psychopathology, paranoia, and violent thoughts, feelings, and behaviors than the other two groups.
Auditory Hallucinations and Posttraumatic Stress Disorder Within Schizophrenia and Substance Abuse
A multidimensional assessment of auditory hallucinations within a sample diagnosed with schizophrenia and substance abuse, both with and without comorbid PTSD, suggests a rate of comorbrid PTSD similar to those reported in other studies.
Post-traumatic reactions to psychosis in people with multiple psychotic episodes
Evaluation of evidence for the psychotic subtyping of post-traumatic stress disorder
The results do not support the official psychotic subtyping of PTSD, and suggest that the syndrome could be subtyped in a similar fashion to mood disorders.