Distinguishing reversible from irreversible virus capsid assembly.

  title={Distinguishing reversible from irreversible virus capsid assembly.},
  author={Adam Zlotnick},
  journal={Journal of molecular biology},
  volume={366 1},
Capsids of spherical viruses may be constructed from hundreds or thousands of copies of the major capsid protein(s). These assembly reactions are poorly understood. Here we consider the predicted behavior for assembly where the component reactions have weak association energy and are reversible and compare them to essentially irreversible reactions. The comparisons are based on mass action calculations and the behavior predicted from kinetic simulations where assembly is described as a cascade… CONTINUE READING


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