Distinguishing properties of cells from the myocardial sleeves of the pulmonary veins: a comparison of normal and abnormal pacemakers.

@article{Jones2008DistinguishingPO,
  title={Distinguishing properties of cells from the myocardial sleeves of the pulmonary veins: a comparison of normal and abnormal pacemakers.},
  author={Sandra A. Jones and Mitsuru Yamamoto and James O. Tellez and Rudi Billeter and Mark R. Boyett and Haruo Honjo and Matthew Lancaster},
  journal={Circulation. Arrhythmia and electrophysiology},
  year={2008},
  volume={1 1},
  pages={39-48}
}
BACKGROUND A common source of arrhythmogenic spontaneous activity instigating atrial fibrillation is the myocardial tissue, or sleeves, at the base of the pulmonary veins. This study compared the properties of cells from the myocardial sleeves of the pulmonary veins (PV(m)) with cells from the normal cardiac pacemaker (the sinoatrial node) and regions of the atria. Our objective was to identify key features of these cells that predispose them to becoming the focus of cardiac arrhythmias… CONTINUE READING
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Reconstruction of the patterns of gene expression in the developing mouse heart reveals an architectural arrangement that facilitates the understanding of atrial malformations and arrhythmias

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