Distinguishing pial and laminar gradient-echo BOLD signals at 7 Tesla

  title={Distinguishing pial and laminar gradient-echo BOLD signals at 7 Tesla},
  author={Peter J. Koopmans and Stephan Orzada and Markus Barth and David G. Norris},
Introduction With high field scanners and multi-channel coil arrays becoming more readily available, high resolution fMRI methods may be capable of detecting neural responses at the laminar level. First results in animals indicate that gradient-echo (GE) is not able to depict laminar activation [1-4] and this has been attributed to the large BOLD contribution of the pial veins corrupting the laminar activation profiles. Spin-echo (SE) studies on the other hand have been able to depict layer… CONTINUE READING

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