Distinguishing mirtrons from canonical miRNAs with data exploration and machine learning methods

@inproceedings{Rorbach2018DistinguishingMF,
  title={Distinguishing mirtrons from canonical miRNAs with data exploration and machine learning methods},
  author={Grzegorz Rorbach and Olgierd Unold and Bogumil Konopka},
  booktitle={Scientific Reports},
  year={2018}
}
Mirtrons are non-canonical microRNAs encoded in introns the biogenesis of which starts with splicing. They are not processed by Drosha and enter the canonical pathway at the Exportin-5 level. Mirtrons are much less evolutionary conserved than canonical miRNAs. Due to the differences, canonical miRNA predictors are not applicable to mirtron prediction… CONTINUE READING