Distinguishing between resistance, tolerance and persistence to antibiotic treatment


Antibiotic tolerance is associated with the failure of antibiotic treatment and the relapse of many bacterial infections. However, unlike resistance, which is commonly measured using the minimum inhibitory concentration (MIC) metric, tolerance is poorly characterized, owing to the lack of a similar quantitative indicator. This may lead to the… (More)
DOI: 10.1038/nrmicro.2016.34


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