Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice.

@article{Heck2003DistinguishableLE,
  title={Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice.},
  author={Susanne Heck and Olga Ermakova and Hiromi Iwasaki and Koichi Akashi and Chiao-Wang Sun and Thomas M Ryan and Tim M. Townes and Thomas Graf},
  journal={Blood},
  year={2003},
  volume={101 3},
  pages={
          903-6
        }
}
We previously described a mouse line that contains green myelomonocytic cells due to the knock-in of enhanced green fluorescence protein (EGFP) into the lysozyme M gene.(1) We have now created a transgenic line with fluorescent erythroid cells using a beta-globin locus control region driving the enhanced cyan fluorescence protein (ECFP) gene. These mice exhibit cyan fluorescent cells specifically in the erythroid compartment and in megakaryocyte-erythroid progenitors. Crossing the animals with… CONTINUE READING

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