Distinctive population of Gfap-expressing neural progenitors arising around the dentate notch migrate and form the granule cell layer in the developing hippocampus.

@article{Seki2014DistinctivePO,
  title={Distinctive population of Gfap-expressing neural progenitors arising around the dentate notch migrate and form the granule cell layer in the developing hippocampus.},
  author={Tatsunori Seki and Toru Sato and Keiko Toda and Noriko Osumi and Tetsuya Imura and Seiji Shioda},
  journal={The Journal of comparative neurology},
  year={2014},
  volume={522 2},
  pages={261-83}
}
In the adult hippocampus, granule cells continue to be generated from astrocyte-like progenitors expressing glial fibrillary acidic protein (GFAP) that differ from embryonic neocortical progenitors. However, during the embryonic period, dentate granule neurons and neocortical pyramidal neurons are derived from the ventricular zone (VZ) of the pallium. Our question is when do GFAP+ progenitors of granule neurons appear in the developing hippocampus during the embryonic period, and how do they… CONTINUE READING
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