Distinctive microRNA signature associated of neoplasms with the Wnt/β-catenin signaling pathway.

@article{Sun2013DistinctiveMS,
  title={Distinctive microRNA signature associated of neoplasms with the Wnt/β-catenin signaling pathway.},
  author={Xu Sun and Yong He and Chen Huang and Tao-tao Ma and Jun Li},
  journal={Cellular signalling},
  year={2013},
  volume={25 12},
  pages={2805-11}
}
As the crucial biological regulators, microRNAs that act by suppressing their target genes are involved in a variety of pathophysiological processes. It is generally accepted that microRNAs are often dysregulated in many types of neoplasm and other human diseases. In neoplasm, microRNAs may function as oncogenes or tumor suppressors. As constitutive activation of the Wnt signaling pathway is a common feature of neoplasm and contributes to its development, progression and metastasis in various… CONTINUE READING
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