Distinctive localization and MRI features correlate of molecular subgroups in adult medulloblastoma

@article{Zhao2017DistinctiveLA,
  title={Distinctive localization and MRI features correlate of molecular subgroups in adult medulloblastoma},
  author={Fu Sheng Zhao and Chunde Li and Qiangyi Zhou and Peiran Qu and Bo Wang and Xin Wang and Shun Zhang and Xingchao Wang and Chi Yun Zhao and Jing Zhang and Lin Luo and Lin Ai and Lei Xu and Pinan Liu},
  journal={Journal of Neuro-Oncology},
  year={2017},
  volume={135},
  pages={353-360}
}
Medulloblastoma (MB) is recognized as comprising four molecular subgroups with distinct transcriptional profiles, clinical features, and outcomes. Previous studies demonstrate that pediatric MBs present with subgroup-specific MRI manifestations. We hypothesized that combination of anatomical localization and conventional features based on MR imaging can predict these subgroups in adult MBs. MR Imaging manifestations of 125 adult patients with MB were analyzed retrospectively based on pre… CONTINUE READING
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