Distinctive Profiles of Gene Expression in the Human Nucleus Accumbens Associated with Cocaine and Heroin Abuse

@article{Albertson2006DistinctivePO,
  title={Distinctive Profiles of Gene Expression in the Human Nucleus Accumbens Associated with Cocaine and Heroin Abuse},
  author={Dawn N Albertson and Carl J. Schmidt and Gregory Kapatos and Michael J Bannon},
  journal={Neuropsychopharmacology},
  year={2006},
  volume={31},
  pages={2304-2312}
}
Drug abuse is thought to induce long-term cellular and behavioral adaptations as a result of alterations in gene expression. Understanding the molecular consequences of addiction may contribute to the development of better treatment strategies. This study utilized high-throughput Affymetrix microarrays to identify gene expression changes in the post-mortem nucleus accumbens of chronic heroin abusers. These data were analyzed independently and in relation to our previously reported data… CONTINUE READING

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