Distinction of eosinophilic leukaemia from idiopathic hypereosinophilic syndrome by analysis of Wilms' tumour gene expression.

@article{Menssen1998DistinctionOE,
  title={Distinction of eosinophilic leukaemia from idiopathic hypereosinophilic syndrome by analysis of Wilms' tumour gene expression.},
  author={Hans Dietrich Menssen and H J Renkl and Harald Rieder and Susanne Bartelt and Aline Schmidt and Michael Notter and Eckhard Thiel},
  journal={British journal of haematology},
  year={1998},
  volume={101 2},
  pages={325-34}
}
In patients presenting with immature eosinophilic precursors it is notoriously difficult to distinguish acute eosinophilic leukaemia (EoL) from the benign idiopathic hypereosinophilic syndrome (HES), based on morphological, cytochemical and immunophenotyping criteria, alone. Cytogenetic analysis or fluorescence in situ hybridization (FISH) can help in discriminating between these rare haematological disorders, but often treatment decisions cannot wait for the results of these time-consuming… CONTINUE READING

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