Distinct thymocyte subsets express the vanilloid receptor VR1 that mediates capsaicin-induced apoptotic cell death

Abstract

AbstractHerein, we provide the first evidence on the capsaicin (CPS) receptor vanilloid receptor type-1 (VR1) by rat thymocytes, and its involvement in CPS-induced apoptosis. VR1 mRNA was identified by quantitative RT-PCR in CD5+ thymocytes. By immunofluorescence and flow cytometry, we found that a substantial portion of CD5+ thymocytes, namely CD4+ and… (More)
DOI: 10.1038/sj.cdd.4401506

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@article{Amantini2004DistinctTS, title={Distinct thymocyte subsets express the vanilloid receptor VR1 that mediates capsaicin-induced apoptotic cell death}, author={Consuelo Amantini and Monica Mosca and Roberta Lucciarini and Marina Cecilia Perfumi and Stefania Morrone and Matthew Piccoli and Giorgio Santoni}, journal={Cell Death and Differentiation}, year={2004}, volume={11}, pages={1342-1356} }