Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor.

@article{PetjRepo2006DistinctSL,
  title={Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor.},
  author={Ulla E. Pet{\"a}j{\"a}-Repo and Mireille Hogue and Tarja T Leskel{\"a} and Piia Markkanen and Jussi Tuusa and Michel Bouvier},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 23},
  pages={
          15780-9
        }
}
Protein palmitoylation is a reversible lipid modification that plays important roles for many proteins involved in signal transduction, but relatively little is known about the regulation of this modification and the cellular location where it occurs. We demonstrate that the human delta opioid receptor is palmitoylated at two distinct cellular locations in human embryonic kidney 293 cells and undergoes dynamic regulation at one of these sites. Although palmitoylation could be readily observed… CONTINUE READING

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