Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

@article{Dewulf1995DistinctSA,
  title={Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.},
  author={Nathalie Dewulf and Kristin Verschueren and Olivier Lonnoy and Anita Mor{\'e}n and Susanne Grimsby and K Vande Spiegle and Kohei Miyazono and Danny Huylebroeck and Peter Ten Dijke},
  journal={Endocrinology},
  year={1995},
  volume={136 6},
  pages={2652-63}
}
Bone morphogenetic proteins (BMPs) are multifunctional proteins structurally related to transforming growth factor-beta (TGF beta) and activin that can induce cartilage and bone growth in vivo. Members of the TGF beta superfamily exert their biological effects via heteromeric serine/threonine kinase complexes of type I and type II receptors. We previously obtained six different type I receptors, termed activin receptor-like kinase-1 (ALK-1) to -6. ALK-5 is a TGF beta type I receptor, ALK-2 and… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 119 extracted citations

Similar Papers

Loading similar papers…