Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.

  title={Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.},
  author={Jennifer M Bates and Erika K. Mittge and Julie Kuhlman and Katrina N Baden and Sarah E. Cheesman and Karen Guillemin},
  journal={Developmental biology},
  volume={297 2},
All animals exist in intimate associations with microorganisms that play important roles in the hosts' normal development and tissue physiology. In vertebrates, the most populous and complex community of microbes resides in the digestive tract. Here, we describe the establishment of the gut microbiota and its role in digestive tract differentiation in the zebrafish model vertebrate, Danio rerio. We find that in the absence of the microbiota, the gut epithelium is arrested in aspects of its… CONTINUE READING
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Formation of the digestive system in zebrafish: III. Intestinal epithelium

  • A. N. Ng, T. A. de Jong-Curtain, +6 authors J. K. Heath
  • morphogenesis. Dev. Biol
  • 2005
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