Distinct signalling pathways for mutated KIT(V560G) and KIT(D816V) in mastocytosis.

Abstract

BACKGROUND The activating mutations KIT(V560G) and KIT(D816V) are associated with mastocytosis. Thus, identifying and inhibiting the signalling pathways associated with mutated KIT gene offers a potentially important strategy for the treatment of mastocytosis. AIM To correlate KIT mutations with specific signalling pathways in human mast-cell lines using… (More)
DOI: 10.1111/ced.12000

Topics

Cite this paper

@article{Chan2013DistinctSP, title={Distinct signalling pathways for mutated KIT(V560G) and KIT(D816V) in mastocytosis.}, author={Ien Chan and Sarah Kasprowicz and Michael D. Tharp}, journal={Clinical and experimental dermatology}, year={2013}, volume={38 5}, pages={538-44} }