Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis.

@article{Ilan1998DistinctST,
  title={Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis.},
  author={Nitza Ilan and Sepi Mahooti and Joseph A. Madri},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 24)},
  pages={3621-31}
}
Angiogenesis, the formation of new blood vessels from pre-existing ones, occurs during development, wound healing and cancer and involves stages that orchestrate a network of cooperative interactions. Peptide growth factors and extracellular matrix (ECM) components are two major groups of angiogenesis mediators. Among the different ECM proteins, collagens have been well-associated with in vivo angiogenesis. Using human umbilical vein endothelial cells (HUVEC) grown in 3-D collagen gels we show… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 95 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 82 references

Similar Papers

Loading similar papers…