Distinct roles of prostaglandin D2 receptors in chronic skin inflammation.

@article{Matsushima2011DistinctRO,
  title={Distinct roles of prostaglandin D2 receptors in chronic skin inflammation.},
  author={Yuki Matsushima and Takahiro Satoh and Yoshihiro Yamamoto and Masataka Nakamura and Hiroo Yokozeki},
  journal={Molecular immunology},
  year={2011},
  volume={49 1-2},
  pages={304-10}
}
Prostaglandin D2 (PGD2) is a prostanoid implicated in allergic inflammation. However, the roles of PGD2 in immune and allergic responses remain controversial. PGD2 exerts its effect through the CRTH2 and DP receptors. To elucidate functional differences of PGD2 and its receptors in chronic skin inflammation, chronic contact hypersensitivity (chronic CHS… CONTINUE READING