Distinct roles of dopamine D3 receptors in modulating methamphetamine-induced behavioral sensitization and ultrastructural plasticity in the shell of the nucleus accumbens.

@article{Zhu2012DistinctRO,
  title={Distinct roles of dopamine D3 receptors in modulating methamphetamine-induced behavioral sensitization and ultrastructural plasticity in the shell of the nucleus accumbens.},
  author={Jie Zhu and Yanjiong Chen and Na Zhao and Guofen Cao and Yonghui Dang and Wei Han and Ming Xu and Teng Chen},
  journal={Journal of neuroscience research},
  year={2012},
  volume={90 4},
  pages={895-904}
}
Persistent changes in behavior and psychological function that occur as a consequence of exposure to drugs of abuse are thought to be mediated by the structural plasticity of specific neural circuits such as the brain's dopamine (DA) system. Changes in dendritic morphology in the nucleus accumbens (NAc) accompany drug-induced enduring behavioral and molecular changes, yet ultrastructural changes in synapses following repeated exposure to drugs have not been well studied. The current study… CONTINUE READING
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