Distinct roles for sequences upstream of and downstream from Physarum editing sites.

Abstract

RNAs in the mitochondria of Physarum polycephalum contain nonencoded nucleotides that are added during RNA synthesis. Essentially all steady-state RNAs are accurately and fully edited, yet the signals guiding these precise nucleotide insertions are presently unknown. To localize the regions of the template that are required for editing, we constructed a… (More)
DOI: 10.1261/rna.1668309

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