Distinct protease pathways control cell shape and apoptosis in v-src-transformed quail neuroretina cells.

@article{Nel2005DistinctPP,
  title={Distinct protease pathways control cell shape and apoptosis in v-src-transformed quail neuroretina cells.},
  author={Benjamin D N{\'e}el and Abdel Aouacheria and Anne-Laure Nouvion and Xavier Ronot and Germain Gillet},
  journal={Experimental cell research},
  year={2005},
  volume={311 1},
  pages={106-16}
}
Intracellular proteases play key roles in cell differentiation, proliferation and apoptosis. In nerve cells, little is known about their relative contribution to the pathways which control cell physiology, including cell death. Neoplastic transformation of avian neuroretina cells by p60(v-src) tyrosine kinase results in dramatic morphological changes and deregulation of apoptosis. To identify the proteases involved in the cellular response to p60(v-src), we evaluated the effect of specific… CONTINUE READING