Distinct presynaptic and postsynaptic dismantling processes of Drosophila neuromuscular junctions during metamorphosis.

@article{Liu2010DistinctPA,
  title={Distinct presynaptic and postsynaptic dismantling processes of Drosophila neuromuscular junctions during metamorphosis.},
  author={Zhiwei Liu and Yan Chen and Dan Wang and Songyan Wang and Yong Q Zhang},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 35},
  pages={11624-34}
}
Synapse remodeling is a widespread and fundamental process that underlies the formation of neuronal circuitry during development and in adaptation to physiological and/or environmental changes. However, the mechanisms of synapse remodeling are poorly understood. Synapses at the neuromuscular junction (NMJ) in Drosophila larvae undergo dramatic and extensive remodeling during metamorphosis to generate adult-specific synapses. To explore the molecular and cellular processes of synapse elimination… CONTINUE READING

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