Distinct phases of coordinated early and late gene expression in growth plate chondrocytes in relationship to cell proliferation, matrix assembly, remodeling, and cell differentiation.

@article{Tchetina2003DistinctPO,
  title={Distinct phases of coordinated early and late gene expression in growth plate chondrocytes in relationship to cell proliferation, matrix assembly, remodeling, and cell differentiation.},
  author={Elena V Tchetina and Fackson Mwale and A. Robin Poole},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2003},
  volume={18 5},
  pages={844-51}
}
Although much has been learned about growth plate development and chondrocyte gene expression during cellular maturation and matrix remodeling in the mouse, there has been a limited study of the interrelationships of gene expression between proteinases, growth factors, and other regulatory molecules in the mouse and in other species. Here we use RT-PCR of… CONTINUE READING