Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate.

@article{Aharoni2011DistinctPP,
  title={Distinct pathological patterns in relapsing-remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate.},
  author={Rina Aharoni and Anya Vainshtein and Ariel Stock and Raya Eilam and Renana From and Vera Shinder and Ruth Arnon},
  journal={Journal of autoimmunity},
  year={2011},
  volume={37 3},
  pages={228-41}
}
The respective roles of inflammatory and neurodegenerative processes in the pathology of multiple sclerosis (MS) and in its animal model experimental autoimmune encephalomyelitis (EAE) are controversial. Novel treatment strategies aim to operate within the CNS to induce neuroprotection and repair processes in addition to their anti-inflammatory properties. In this study we analyzed and compared the in situ pathological manifestations of EAE utilizing two different models, namely the relapsing… CONTINUE READING
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