Distinct ontogenic patterns of overt and latent DGAT activities of rat liver microsomes.

@article{Waterman2002DistinctOP,
  title={Distinct ontogenic patterns of overt and latent DGAT activities of rat liver microsomes.},
  author={Ian J Waterman and Nigel T. Price and Victor A. Zammit},
  journal={Journal of lipid research},
  year={2002},
  volume={43 9},
  pages={1555-62}
}
We have studied the ontogeny of the two functional diacylglycerol acyltransferase (DGAT) activities (overt and latent) during postnatal development in rat liver. We find that the ontogenic patterns of the two are highly distinct. Overt DGAT shows a transient rise in activity up to day 4 postnatally, after which it declines until weaning; thereafter, it increases steadily to reach high adult values that may contribute to the high rates of turnover of cytosolic triacylglycerol (TAG). By contrast… CONTINUE READING

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