Distinct miRNA signatures associate with subtypes of cholangiocarcinoma from infection with the tumourigenic liver fluke Opisthorchis viverrini.

@article{Plieskatt2014DistinctMS,
  title={Distinct miRNA signatures associate with subtypes of cholangiocarcinoma from infection with the tumourigenic liver fluke Opisthorchis viverrini.},
  author={Jordan L. Plieskatt and Gabriel Rinaldi and Yanjung Feng and Jin Peng and Ponlapat Yonglitthipagon and Samantha E. Easley and Therawach Laha and Chawalit Pairojkul and Vajarabhongsa Bhudhisawasdi and Banchob Sripa and Paul J. Brindley and Jason P. Mulvenna and Jeffrey Michael Bethony},
  journal={Journal of hepatology},
  year={2014},
  volume={61 4},
  pages={850-8}
}
BACKGROUND & AIMS Intrahepatic cholangiocarcinoma (ICC) is a significant public health problem in East Asia, where it is strongly associated with chronic infection by the food-borne parasite Opisthorchis viverrini (OV). We report the first comprehensive miRNA expression profiling by microarray of the most common histologic grades and subtypes of ICC: well differentiated, moderately differentiated, and papillary ICC. METHODS MicroRNA expression profiles from FFPE were compared among the… CONTINUE READING
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