Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs.

@article{Tonkonogy1993DistinctLP,
  title={Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs.},
  author={Susan L. Tonkonogy and Susan L Swain},
  journal={Immunology},
  year={1993},
  volume={80 4},
  pages={574-80}
}
We have investigated the potential of CD4+ T cells isolated from Peyer's patches and mesenteric lymph nodes (mucosa-associated lymphoid tissues) and from spleens and peripheral lymph nodes (systemic lymphoid tissues) to secrete a variety of lymphokines. The results show several pronounced differences in the kinetics of lymphokine production and in the… CONTINUE READING