Distinct host cell fates for human malignant melanoma targeted by oncolytic rodent parvoviruses.

Abstract

The rodent parvoviruses are known to be oncoselective, and lytically infect many transformed human cells. Because current therapeutic regimens for metastatic melanoma have low response rates and have little effect on improving survival, this disease is a prime candidate for novel approaches to therapy, including oncolytic parvoviruses. Screening of low… (More)
DOI: 10.1016/j.virol.2013.07.013

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