Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data

@article{Tong2008DistinctGS,
  title={Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data},
  author={Louis Tong and Jaime Chew and Henry He Yang and Leonard Pek-Kiang Ang and Donald Tiang Hwee Tan and Roger W. Beuerman},
  journal={BMC Medical Genomics},
  year={2008},
  volume={2},
  pages={14 - 14}
}
Pterygium is a common ocular surface disease characterized by fibrovascular invasion of the cornea and is sight-threatening due to astigmatism, tear film disturbance, or occlusion of the visual axis. However, the mechanisms for formation and post-surgical recurrence of pterygium are not understood, and a valid animal model does not exist. Here, we investigated the possible mechanisms of pterygium pathogenesis and recurrence. First we performed a genome wide expression analysis (human Affymetrix… CONTINUE READING
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