Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes

Abstract

We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1(hi) ) or non-classical (resident/Gr1(lo) ) monocytes to dissect their differential role in atheroprogression under high-fat diet (HFD). Apolipoprotein E-deficient (Apoe(-/-) ) mice lacking classical but… (More)
DOI: 10.1002/emmm.201201717

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@inproceedings{Soehnlein2013DistinctFO, title={Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes}, author={Oliver Soehnlein and Maik D Drechsler and Yvonne D{\"{o}ring and Dirk Lievens and Helene Hartwig and Klaus Kemmerich and Almudena Ortega-G{\'o}mez and Manuela Mandl and Santosh Vijayan and Delia Projahn and Christoph D. Garlichs and Rory R Koenen and Mihail Hristov and Esther Lutgens and Alma Zernecke and Christian Weber}, booktitle={EMBO molecular medicine}, year={2013} }