Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.

@article{Chan2012DistinctEP,
  title={Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.},
  author={Melissa V Chan and Kristen J. Bubb and Alastair John Noyce and Inmaculada C Villar and Johan Duchene and Adrian J Hobbs and Ramona S. Scotland and Amrita Ahluwalia},
  journal={British journal of pharmacology},
  year={2012},
  volume={167 4},
  pages={805-17}
}
BACKGROUND AND PURPOSE Pre-menopausal females have a lower incidence of cardiovascular disease compared with age-matched males, implying differences in the mechanisms and pathways regulating vasoactivity. In small arteries, myogenic tone (constriction in response to raised intraluminal pressure) is a major determinant of vascular resistance. Endothelium… CONTINUE READING